Skin cancer is a worldwide heterogeneous collection of cancers compromising melanoma and non-melanoma, predominantly affecting geriatric patients ages 65 and older, and represents a challenge in clinical management [5]. Mohs micrographic surgery (MMS) is a clinical procedure implemented in the treatment of various forms of non-melanoma and melanoma skin cancers; the process involves removing thin layers of visible cancer tissue and analyzing the tissue margins until all cancerous tissue has been removed [18]. To date, there exists no standard for postoperative wound management following MMS; to achieve optimal recovery, the patient and surgeon have a myriad of available options for treatment. This retrospective clinical case study demonstrates the effectiveness of dehydrated human amniotic membrane allografts (Axolotl DualGraft™) as a treatment modality for successful wound closure and healing in various post-Mohs secondary intention wounds. A plastics reconstructive surgeon with Heartland Plastic & Reconstructive Surgery P.C. utilized amniotic membrane (AM) allograft as a vulnerary modality for distinctive post-Mohs wounds from diverse geriatric patients. Further investigation for the optimal application in a controlled study using dehydrated amnion-amnion membrane for post-Mohs surgical wounds should be considered based on these data